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We are pleased to share with you our complet webinars on Multi-Omics :
Simultaneous single-cell mRNA and epitope mapping of human CD4+ T-cells using the BD Rhapsody™ and the BD™ AbSeq platform
“ Currently a senior post-doctoral fellow in John Todd’s lab at the University of Oxford, my primary research aims at understanding how type 1 diabetes-associated genetic variants are functionally associated with disease. Through a combination of genomic and flow cytometric approaches, I have been interested in characterising the regulatory T-cell compartment in type 1 diabetes, and how it is modulated by low-dose IL-2 treatment in vivo. More recently, I have been interested in the application of single-cell RNA sequencing technologies, including the BD Rhapsody™ system, as a powerful new approach to dissect the heterogeneity of regulatory T cells in humans.”
Dr Ricardo C. Ferreira, University of Oxford
Evolution, challenges and the future of single-cell immunology
In this webinar, the second in the series of the BD Multi-Omics user day presentations, Christina Chang talks about how the BD single-cell, end-to-end workflow with informatics helps to increase the experimental power available to researchers. This workflow comprises of sample preparation, single-cell isolation and molecular barcoding, library preparation, sequencing and data analysis. Watch the webinar to learn how the BD® AbSeq, BD Rhapsody™ platform, Targeted RNA-seq Panels and SeqGeq™/FlowJo™ give researchers greater flexibility in workflow and experimental design. Possibilities using this workflow include the detection of changes in protein similar to flow-cytometry, revealing of new cell-clusters through the addition of protein information to mRNA data, kinetic analysis of mRNA and protein dynamics and biomarker discovery.
Christina Chang, PhD
Interested to read publication on Multi-Omics ?
We’ve selected few for you
A targeted multi-omic analysis approach measures protein expression and low abundance transcripts on the single cell level
Florian Mair, Jami R. Erickson, Valentin Voillet, Yannick Simoni, Timothy Bi, Aaron J. Tyznik, Jody Martin, Raphael Gottardo, Evan W. Newell, Martin Prlic
Simultaneous mRNA and protein quantification at the single-cell level delineates trajectories of CD4+ T-cell differentiation
Dominik Trzupek, Melanie Dunstan, Antony J. Cutler, Mercede Lee, Leila Godfrey, Dominik Aschenbrenner, Holm H. Uhlig, Linda S. Wicker, John A. Todd, Ricardo C. Ferreira
A novel antibody targeting ICOS increases intratumoural cytotoxic to regulatory T cell ratio and induces tumour regression
Richard C.A. Sainson, Anil K. Thotakura, Miha Kosmac, Gwenoline Borhis, Nahida Parveen, Rachael Kimber, Joana Carvalho, Simon Henderson, Kerstin Pryke, Tracey Okell, Siobhan O’Leary, Stuart Ball, Lauriane Gamand, Emma Taggart, Eleanor Pring, Hanif Ali, Hannah Craig, Vivian W. Y. Wong, Qi Liang, Robert J. Rowlands, Morgane Lecointre, Jamie Campbell, Ian Kirby, David Melvin, Volker Germaschewski, Elisabeth Oelmann, Sonia Quaratino, Matthew McCourt
Reliability of human cortical organoid generation.
Yoon SJ, Elahi LS, Pașca AM, Marton RM, Gordon A, Revah O, Miura Y, Walczak EM, Holdgate GM, Fan HC, Huguenard JR, Geschwind DH, Pașca SP.
